Mitochondrial Dysfunction PDF
By:Lawrence H. Lash,Dean P. Jones
Published on 2013-10-22 by Elsevier
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
This Book was ranked at 34 by Google Books for keyword Toxicology.
Book ID of Mitochondrial Dysfunction's Books is SRAlBQAAQBAJ, Book which was written byLawrence H. Lash,Dean P. Joneshave ETAG "kLedwNFaMXM"
Book which was published by Elsevier since 2013-10-22 have ISBNs, ISBN 13 Code is 9781483218618 and ISBN 10 Code is 1483218619
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Book which have "528 Pages" is Printed at BOOK under CategoryScience
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